The Potential Role of RT-LAMP in SARS-CoV-2 Diagnosis Based on Limit of Detection

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, that arose in 2019 underscored significance of testing and diagnostics order to combat rapid spread disease. most common method for SARS-CoV-2 RNA detection has been RT-qPCR method, which is insufficient terms meeting immense demand due its relatively high time-consumption. Under these circumstances, urgent need a similarly sensitive arised, RT-LAMP was proven be promising alternative. This review compares lowest concentration levels two mentioned methods can detect, examining several reviews research. It found limit lower comparison RT-LAMP, demonstrates higher sensitivity, thus, reducing false negative outcomes. Nonetheless, more convenient being deployed as point-of-care test vast amounts people considering rapidity simplicity, albeit it compared RT-qPCR.